Charles E Dann Selected Research

glycinamide ribonucleotide

1/2021	Discovery of 6-substituted thieno[2,3-d]pyrimidine analogs as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis in folate receptor expressing human tumors.
1/2017	Correction to Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase.
1/2016	Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase.

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Charles E Dann Research Topics

Disease

7	Neoplasms (Cancer) 01/2021 - 09/2013
1	Anthrax 01/2021
1	Inflammation (Inflammations) 09/2013
1	Alzheimer Disease (Alzheimer's Disease) 08/2012
1	Severe Acute Respiratory Syndrome 12/2009
1	Hypoxia (Hypoxemia) 11/2002

Drug/Important Bio-Agent (IBA)

5	Folic Acid AntagonistsIBA 01/2017 - 09/2013
4	Folic Acid (Vitamin M)FDA LinkGeneric 01/2021 - 09/2013
3	Hydroxymethyl and Formyl TransferasesIBA 01/2021 - 01/2016
3	EnzymesIBA 01/2021 - 09/2013
3	pyrimidineIBA 01/2021 - 09/2015
3	glycinamide ribonucleotideIBA 01/2021 - 01/2016
2	NucleotidesIBA 01/2021 - 01/2016
2	Proteins (Proteins, Gene)FDA Link 01/2021 - 12/2009
2	purineIBA 01/2021 - 01/2016
2	Proton-Coupled Folate TransporterIBA 01/2016 - 09/2015
1	ThiophenesIBA 01/2021
1	furanIBA 01/2021
1	CarbonIBA 01/2021
1	RibonucleotidesIBA 01/2021
1	NAD (NADH)IBA 10/2019
1	Adenosine Triphosphate (ATP)IBA 10/2019
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 10/2019
1	Glycine Hydroxymethyltransferase (Serine Hydroxymethyltransferase)IBA 10/2019
1	Methotrexate (Mexate)FDA LinkGeneric 01/2016
1	Pemetrexed (MTA)FDA Link 01/2016
1	Reduced Folate Carrier ProteinIBA 09/2015
1	LipidsIBA 08/2012
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 08/2012
1	Peptides (Polypeptides)IBA 08/2012
1	Amyloid (Amyloid Fibrils)IBA 08/2012
1	RNA (Ribonucleic Acid)IBA 12/2009
1	Oxygen (Dioxygen)IBA 11/2002
1	Transcription Factors (Transcription Factor)IBA 11/2002

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 01/2016